BREATHE IN NEW TECH
BREATHE
OUT ANIMAL TESTING
RESPIRE™
3D Bioprinted Lung Microtissues
Frontier Bio's proprietary technology allows bioprinting of some of the most complex human tissues.
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Our newest developments in bioprinting led us to recreate the fundamental units of the complex human lung - the branching bronchioles, the alveolar airsacs, and the vasculature.
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We envision our technology to be key in answering unmet needs in the three areas below.
KEY AREAS OF APPLICATION
BIODEFENSE
Animal models have been the gold standard in host-pathogen testing even though infection is highly specific to the host.
RESPIRE™ mimics the natural response of human lungs to infectious agents.
THERAPEUTIC
TESTING
Elevate your respiratory drug development using RESPIRE™.
Using our complex model, you can weed out non-efficacious drugs from your pipeline.
DEVELOPMENTAL
STUDIES
Assess toxicity of your drug candidates to prevent complications with the respiratory tract such as fibrosis and common side effects.
ADVANTAGES
RESPIRE™ 3D printed lungs bridges the gap between simpler in vitro respiratory models (organoid and organ-on-chip technologies) and whole animals. It is a full distal lung model containing the bronchial and alveolar epithelia and their associated mesenchymal and vascular cells. Since it's comprised of human cells, RESPIRE™ is expected to perform similarly to the human distal lung. This makes it indispensable in research where animal models fail to mimic human-like responses, such as in viral infections.
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