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3D BIOPRINTEDLUNG MICROTISSUE

Revolutionizing respiratory health through the power of stem cells and 3D bioprinting.

Creating complex tissue by combining 3D bioprinting with the power of self-assembly. We call our lung microtissue: RESIPIRE.

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Our newest developments in bioprinting led us to recreate the fundamental units of the complex human lung - the bronchioles, the alveolar airsacs, and the vasculature.​ We envision our technology to be key in answering unmet needs in various application areas.

Key Areas of Application

BIODEFENSE

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Investigate how pathogens interact with lung tissue and enhance protective strategies.

THERAPEUTICS
TESTING

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Quickly weed out non-efficacious drug candidates using our high-fidelity human model.​​

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DEVELOPMENTAL
STUDIES

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Assess toxicity of drug candidates to prevent complications with the respiratory tract such as fibrosis. 

Advantages

RESPIRE™ 3D printed lungs bridge the gap between simpler in vitro respiratory models (organoid and organ-on-chip technologies) and whole animals. It is a full distal lung model containing the bronchial and alveolar epithelia and their  associated mesenchymal and vascular cells. Since it's comprised of human cells, RESPIRE™ is expected to perform similarly to the human distal lung. This makes it indispensable in research where animal models fail to mimic human-like responses, such as in viral infections.

Bridging the Organ Shortage with Bioprinted Lungs

The average cost of a lung transplant in the US can range from $900k to $1.2M. Furthermore, the 5-year survival rate after a lung transplant is 50-60%.

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This needs to change. Frontier Bio is working towards the creation of lab-grown human lungs that will lead to safer and more affordable transplants.

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Reach out to explore collaboration & partnership possibilities

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