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BREATHE IN NEW TECH

BREATHE

OUT ANIMAL TESTING

RESPIRE™

3D Bioprinted Lung Microtissues

Frontier Bio's proprietary technology allows bioprinting of some of the most complex human tissues.

Our newest developments in bioprinting led us to recreate the fundamental units of the complex human lung - the branching bronchioles, the alveolar airsacs, and the vasculature.

We envision our technology to be key in answering unmet needs in the three areas below.

KEY AREAS OF APPLICATION

BIODEFENSE

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Animal models have been the gold standard in host-pathogen testing even though infection is highly specific to the host. 

 

RESPIRE™ mimics the natural response of human lungs to infectious agents.

THERAPEUTIC
TESTING

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Elevate your respiratory drug development using RESPIRE™.

 

Using our complex model, you can weed out non-efficacious drugs from your pipeline.

DEVELOPMENTAL
STUDIES

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Assess toxicity of your drug candidates to prevent complications with the respiratory tract such as fibrosis and common side effects. 

ADVANTAGES

RESPIRE™ 3D printed lungs bridges the gap between simpler in vitro respiratory models (organoid and organ-on-chip technologies) and whole animals. It is a full distal lung model containing the bronchial and alveolar epithelia and their  associated mesenchymal and vascular cells. Since it's comprised of human cells, RESPIRE™ is expected to perform similarly to the human distal lung. This makes it indispensable in research where animal models fail to mimic human-like responses, such as in viral infections.

Reach out to explore collaboration & partnership possibilities

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